Method of nephroscintigraphic dynamic images analysis
Gaidel A.V., Kapishnikov A.V., Pyshkina Yu.S., Kolsanov A.V., Khramov A.G.

 

Samara National Research University, 443086, Russia, Samara, Moskovskoye shosse 34,
IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS, 443001, Samara, Russia, Molodogvardeyskaya 151,
Samara State Medical University, Samara, Russia

Abstract:
We propose a method for automatic processing of dynamic nephroscintigrams based on fitting the renogram curve by an exponential function. The method makes it possible to obtain objective parameters of the kidney condition. The performance of the method is studied on a set of radionuclide images of a transplant. Results of clinical studies confirming the diagnostic efficiency of the developed approach are presented. Analysis of the kinetics of the nephrotropic indicator provides an accurate assessment of the functional status of the transplanted kidney. Two numerical parameters are revealed that offer a higher diagnostic efficiency when calculated from the constructed model compared to when they are calculated from the original renogram.

Keywords:
image processing, pattern recognition, scintigraphy, nephrology, transplantation.

Citation:
Gaidel AV, Kapishnikov AV, Pyshkina YuS, Kolsanov AV, Khramov AG. Method of nephroscintigraphic dynamic images analysis. Computer Optics 2018; 42(4): 688-694. DOI: 10.18287/2412-6179-2018-42-4-688-694.

References:

  1. Stolyarevich ES, Artyuhina LY, Kim IG, Kurenkova LG, Tomilina NA. Late kidney allograft rejection: the impact of pathology on the long-term outcome [In Russian]. Nephrology and dialysis 2012; 14(4): 242-252.
  2. Kraynik NA, Sandrikov VA, Sadovnikov VI, Kaabak MM, Platova EN. Intraoperative ultrasound monitoring of renal allograft [In Russian]. Ultrasonic and functional diagnostics 2016; 3: 11-24.
  3. Lishmanov YuB, Chernov VI, eds. Radionuclide diagnostics for practitioners [In Russian]. Tomsk: “STT” Publisher; 2004. ISBN: 5-93629-166-9.
  4. Kotina ED, Ovsyannikov DA, Ploskikh VA, Babin AV, Tuzikova OF. Data processing in radionuclide diagnostics [In Russian]. Ulyanovsk medical and biological journal 2014; 1: 174-175.
  5. Williams DL. Improvement in quantitative data analyses by numerical deconvolution techniques. J Nucl Med 1979; 20(6): 568-557.
  6. Lee S, Lee К, Shin S, Park Y. Generalized image deconvolution by exploiting the transmission matrix of an optical imaging system. Sci Rep 2017; 7(1): 8961. DOI: 10.1038/s41598-017-07937-8.
  7. Chaiwatanarat T, Laorpatanaskul S, Poshyachinda M, Boonvisut S, Buachum V, Krisanachinda A, Suvanapha R. Deconvolution analysis of renal blood flow: evaluation of postrenal transplant complications. J Nucl Med 1994; 35(11):1792-1796.
  8. Cosgriff PS. The urinary tract. In Book: Sharp PF, Gemmell HG, Murray AD, eds. Practical nuclear medicine. Pt 11. London: Springer; 2005: 205-230. DOI: 10.1007/1-84628-018-4_11.
  9. Durand E, Blaufox MD, Britton KE, Carlsen О, Cosgriff P, Fine E, Fleming J, Nimmon C, Piepsz A, Prigent A, Samal M. International scientific committee of radionuclides in nephrourology (ISCORN) consensus on renal transit time measurements. Semin Nucl Med 2008; 38(1): 82-102. DOI: 10.1053/j.semnuclmed.2007.09.009.
  10. Bajén MT, Puchal R, González А, Grinyó JM, Castelao A, Mora J, Martin-Comin J. MAG3 renogram deconvolution in kidney transplantation: utility of the measurement of initial tracer uptake. J Nucl Med 1997; 38(8): 1295-1299.
  11. Knesaurek K, Spaventi S. Comparison of three deconvolution techniques in renography. Eur J Nucl Med 1984; 9(6): 254-256.
  12. Gaidel AV, Larionova SN, Khramov AG. Research of textural features for the diagnostics of nephrological diseases using ultrasound images [In Russian]. Vestnik of the Samara State Aerospace University 2014; 1(43): 229-237. DOI: 10.18287/1998-6629-2014-0-1(43)-229-237.
  13. Gaidel AV, Khramov AG, Kapishnikov AV, Kolsanov AV, Pyshkina YuS. A method for digital renal scintigram analysis based on brightness and geometric features [In Russian]. Computer Optics 2017; 41(1): 103-109. DOI: 10.18287/2412-6179-2017-41-1-103-109.
  14. Vesnina ZhV. Radionuclide diagnosis in nephrology and urology [In Russian]. In Book: Lishmanov YuB, Chernov VI, eds. Radionuclide diagnostics for practitioners. Tomsk: “STT” Publisher; 2010. Vol 2: 195.
  15. Kuyvenhoven JD, Ham HR, Piepsz A. Optimal time window for measurement of renal output parameters. Nucl Med Rev Cent East Eur 2002; 5(2):105-108.

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